Optical microscopy / spectroscopy research

Advanced spectroscopies and microscopies for biomedical imaging and diagnosis.

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Raman spectroscopy Vibrational spectroscopy provides chemical information from all materials, and is well suited to biological samples. Diagnoses cancerous tissue, and non-invasively characterizes live cells.
Coherent anti-Stokes Raman (CARS) microscopy CARS microscopy gives 4-5 orders of magnitude more signal than standard Raman spectroscopy. Produces high resolution, label-free chemical images of live cells and tissue in seconds.

Multi-photon microscopy / multi-modal microscopy CARS microscopy, two-photon fluorescence (TPF), second harmonic generation (SHG), sum frequency generation (SFG), and fluorescence lifetime imaging (FLIM): all on the same microscope.
Scanning near-field optical microscopy (SNOM) Combining optical spectroscopy with Atomic Force Microscopy to achieve local Raman spectroscopy on the scale of ~10 nm. Nano-scale fluorescence and (coming soon:) CARS microscopy.

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