Optical microscopy / spectroscopy research

 

Advanced spectroscopies and microscopies for biomedical imaging and diagnosis.

 

Click on each theme to find out more.

 

 

Raman spectroscopy

 

Vibrational spectroscopy provides chemical information from all materials, and is well suited to biological samples. Diagnoses cancerous tissue, and non-invasively characterizes live cells.

Coherent anti-Stokes Raman (CARS) microscopy

 

CARS microscopy gives 4-5 orders of magnitude more signal than standard Raman spectroscopy. Produces high resolution, label-free chemical images of live cells and tissue in seconds.

 

Multi-photon microscopy / multi-modal microscopy

 

CARS microscopy, two-photon fluorescence (TPF), second harmonic generation (SHG), sum frequency generation (SFG), and fluorescence lifetime imaging (FLIM): all on the same microscope.

Scanning near-field optical microscopy (SNOM)

 

Combining optical spectroscopy with Atomic Force Microscopy to achieve local Raman spectroscopy on the scale of ~10 nm.

Nano-scale fluorescence and (coming soon:) CARS microscopy.

 

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